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Self-medication of patients using immunosuppressants
Zouharová, Veronika ; Malý, Josef (advisor) ; Babica, Jan (referee)
Self-medication of patients using immunosuppressive drugs Author: Veronika Zouharová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Barbora Košťálová, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy, in Hradec Králové, Charles University Introduction and aims: Self-medication can be used to treat minor health problems without consulting a doctor. The aim of this masters thesis was to analyse the use of potentially risky over- the-counter medicines, dietary supplements or food in patients with a history of kidney disease taking immunosuppressants. Methods: Data for the cross-sectional study were obtained in the form of a controlled interview with patients of the Nephrology Consultation of the Teaching Hospital Hradec Králové. The guided interview was carried out by the researcher in the form of phone calls with patients in March 2022 through a structured questionnaire. The questionnaire was compiled on basis of a literature search and knowledge gained about possible interactions between immunosuppressants and over-the- counter medicinal products, dietary supplements and food. Patients with kidney disease who had been taking at least one immunosuppressant (cyclosporine, azathioprine, mycophenolate, prednisone, tacrolimus or rituximab) for past six months were...
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Lék nebo hrozba? Antropologické perspektivy samoléčby konopím v České republice
Bláhová, Barbora ; Horák, Miroslav (advisor) ; Halbich, Marek (referee)
This diploma thesis focuses specifically on the phenomenon of self-medication with cannabis (Cannabis Sativa L.) in the Czech Republic exploring subjective perception of this treatment by ill persons and its sociocultural framework. It describes a situation when the state fails to effectively regulate medical cannabis and patients often seek practices of self-medication, which remains illegal. Theoretical part of this thesis aims to explain the self- medication and cannabis use in the sociocultural context. Practical part is based on an anthropological research, which was implemented in the Czech Republic from January 1, 2017 to May 1, 2017 in a form of the on-line qualitative questionnaire survey. The research sample consists of 107 subjects, who used cannabis and its derives for self-medication. The analysis was done by the Grounded theory method. The results demonstrate that people who seek cannabis self-medication in the Czech Republic consider current legal regulation of cannabis objectionable. Cannabis plants for self-medication are usually grown at home and people find information about specifics of the treatment on-line. Looking at experience of patients, this thesis describes specifics of the practices of cannabis self-medication and it could be useful for organizations working with...
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The Analysis of Senior's Opinions on Self-treatment by non-steroidal anti-inflamatory drugs I
Čižmárová, Jana ; Doseděl, Martin (advisor) ; Malá, Kateřina (referee)
The Analysis of Senior's Opinions on Self-treatment by non-steroidal anti-inflammatory drugs II Author: Jana Čižmárová Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Department: Department of Social and Clinical Pharmacy Background: Self-medication is a growing trend in a society with widespread use of over- the-counter medicines. Among the OTC medicines, analgesics belong to the drugs with the highest consumption. They are also popular in the group of seniors, who often suffer from chronic pain, mainly of the musculoskeletal system. Aim of study: In the theoretical part to carry out a review of published papers concerning safety of self-medication with analgesics and non-steroidal anti-inflammatory drugs. In the practical part, by performing a questionnaire survey to acquire and analyze the attitudes of seniors regarding self-medication with analgesics and anti-inflammatory drugs focused on ibuprofen. Methods: An observational cross-sectional study was carried out in the facilities for seniors of the Trenčín region. The survey was conducted by interview with senior using questionnaire sheets. The research took place in the period July to September 2019. Results: 64.0 % of seniors suffered from almost every day or daily pain, mainly from musculoskeletal pain. The main counselling subject...
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The Analysis of Senior's Opinions on Self-treatment by non-steroidal anti-inflamatory drugs III
Procházka, Marek ; Doseděl, Martin (advisor) ; Kostřiba, Jan (referee)
The Analysis of Seniors' Opinions on Self-treatment by Non-steroidal Anti-inflamatory Drugs III Charles University, Faculty of Pharmacy in Hradec Králové Department of: Social and Clinical Pharmacy Candidate: Marek Procházka Consultant: PharmDr.Martin Doseděl, Ph.D. Background: Self-treatment is one of the approaches in managing pain which is still gaining higher level of importance even amongst seniors. One of the most favourite over the counter (OTC) analgesics is ibuprofen, however its use can be associated with certain drug related problems (DRP). The potential of DRPs is increasing with age which makes seniors more sensitive to them. Aim of study: 1) To create an overview of DRPs of OTC analgesics, focusing on paracetamol (acetaminophen). 2) Through the survey find out the knowledge and experience of seniors with self-treatment by OTC analgesics. The other aim was to evaluate their sources of information concerning ibuprofen and their preferences to each product. Methods: The observable cross-sectional study was made through social media and in Královéhradecký region. In the first case the questionnaire was spread through social media- Facebook. In the second case standardised conversation with questionnaire lists was applied with seniors above 60 years of age. The research was anonymous and...
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The Analysis of Senior's Opinions on Self-treatment by non-steroidal anti-inflamatory drugs I
Čižmárová, Jana ; Doseděl, Martin (advisor) ; Malá, Kateřina (referee)
The Analysis of Senior's Opinions on Self-treatment by non-steroidal anti-inflammatory drugs II Author: Jana Čižmárová Supervisor of the thesis: PharmDr. Martin Doseděl, Ph.D. Department: Department of Social and Clinical Pharmacy Background: Self-medication is a growing trend in a society with widespread use of over- the-counter medicines. Among the OTC medicines, analgesics belong to the drugs with the highest consumption. They are also popular in the group of seniors, who often suffer from chronic pain, mainly of the musculoskeletal system. Aim of study: In the theoretical part to carry out a review of published papers concerning safety of self-medication with analgesics and non-steroidal anti-inflammatory drugs. In the practical part, by performing a questionnaire survey to acquire and analyze the attitudes of seniors regarding self-medication with analgesics and anti-inflammatory drugs focused on ibuprofen. Methods: An observational cross-sectional study was carried out in the facilities for seniors of the Trenčín region. The survey was conducted by interview with senior using questionnaire sheets. The research took place in the period July to September 2019. Results: 64.0 % of seniors suffered from almost every day or daily pain, mainly from musculoskeletal pain. The main counselling subject...
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The Analysis of Senior's Opinions on Self-treatment by non-steroidal anti-inflamatory drugs
Kliui, Yuliia ; Doseděl, Martin (advisor) ; Zimčíková, Eva (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate: Yuliia Kliui Consultant: PharmDr. Martin Doseděl PhD. Title of the diploma thesis: The Analysis of Senior's Opinions on Self-treatment by non- steroidal anti-inflammatory drugs Introduction: Due to their significant analgesic and antiphlogistic effects are non-steroidal anti-inflammatory drugs one of the most prescribed drugs. According to the high number of side effects and drug-drug interactions, it is important to pay attention to their presence in patient's medication. The importance of drug related problems increases in polymorbid and geriatric patients, who's medication can be altered by the presence of non-steroidal anti-inflammatory drugs, which can lead to unwanted complications. Aim of study: The principal aim of the theoretical part is to elaborate a review of the drug related problems concerning the side effects and drug-drug interactiond of NSAIDs. The practical part analyses via a question-study the senior's opinion and experiences on self- medication by analgesics focusing on ibuprofen. Methods: A cross sectional study have been conducted in the city of Kharkov in Ukraine. The data have been collected during an interview with a questionnaire. The used questionnairre has...
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Lék nebo hrozba? Antropologické perspektivy samoléčby konopím v České republice
Bláhová, Barbora ; Horák, Miroslav (advisor) ; Halbich, Marek (referee)
This diploma thesis focuses specifically on the phenomenon of self-medication with cannabis (Cannabis Sativa L.) in the Czech Republic exploring subjective perception of this treatment by ill persons and its sociocultural framework. It describes a situation when the state fails to effectively regulate medical cannabis and patients often seek practices of self-medication, which remains illegal. Theoretical part of this thesis aims to explain the self- medication and cannabis use in the sociocultural context. Practical part is based on an anthropological research, which was implemented in the Czech Republic from January 1, 2017 to May 1, 2017 in a form of the on-line qualitative questionnaire survey. The research sample consists of 107 subjects, who used cannabis and its derives for self-medication. The analysis was done by the Grounded theory method. The results demonstrate that people who seek cannabis self-medication in the Czech Republic consider current legal regulation of cannabis objectionable. Cannabis plants for self-medication are usually grown at home and people find information about specifics of the treatment on-line. Looking at experience of patients, this thesis describes specifics of the practices of cannabis self-medication and it could be useful for organizations working with...
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ADHD and cannabinoid use as a form of self-medication
Karchňáková, Zuzana ; Vacek, Jaroslav (advisor) ; Svěcená, Kateřina (referee)
BASIC POSTULATES: It is common the people affected by ADHD consume addictive substances, seeking relief from their sensations of motorical unease and to disturb their rationalising and thinking. Using these substances subjectively improves their abilities, reducing the undesired and unpleasant sensations emanating from the ADHD, possibly even creating enjoyable and desirable moods. The resulting problem is, this self-medication causes troubles in many aspects, detectable only gradually after longer periods of consumption. What starts as an effort to paliate the undesirable symptoms of ADHD and other effects thereof, progressively becomes seeking a solution to harmful consumption of marihuana and, in extreme cases, additiction to cannabinoids. OBJECTIVES: The main objective of this thesis is to find out what is the purpose of the people with ADHD diagnosis in taking cannabis. The focus as put on whether cannabis is used to treat the symptoms of ADHD or not (regardless of the diagnosis). It was also important to map what other addictive substances use if self-medication using cannabis. METHODS: Semi-structured was chosen for the purposes of research. The questionnaires were used from L. Adler ASRS -V1 Adler.1 - Report (Adult ADHD Self Scale). Cannabis Use Disorders Identification Test (CUDIT) from...
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The analysis of self-medication with antibiotics in Kaliningrad region - pilote study
Matveicheva, Kira ; Vlček, Jiří (advisor) ; Jílek, Petr (referee)
Abtract Charles University Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Title of diploma thesis: The analysis of self-medication with antibiotics in Kaliningrad region - pilote study Student: Kira Matveicheva Supervisor: prof. PharmDr. Jiří Vlček, Ph.D. Consultant: Tatiana Belkina, Ph.D. Objectives: In the theoretical part, I will focus on the self-medication with antibiotics, including its causes and consequences, and the problems associated with the emergence of antibiotic resistance. The aim of the practical part is to analyze the probability and reasons of self-medication with antibiotics in the Kaliningrad region. Methods: A study was conducted from July-August 2015 of community pharmacists and pharmaceutical assistants in Kaliningrad region, Russia. The theoretical part contains a literature research about self-medication with antibiotics and antibiotic resistance which was performed through using PubMed. The main keywords which were used were: "self- medication; antibiotics use; antimicrobial resistance". In practical part was used a self- administered questinnaire to assess antibiotic dispensing without a medical prescription by pharmacists/ pharmaceutical assistants and causes of self-medication practices. Results: Eighty questionnaires were completed, with a...
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ADHD and cannabinoid use as a form of self-medication
Karchňáková, Zuzana ; Vacek, Jaroslav (advisor) ; Svěcená, Kateřina (referee)
1 Abstract BASIC POSTULATES: It is common the people affected by ADHD consume addictive substances such as alcohol, marihuana, heroin, sedatives, analgetics, nicotine, caffeine, sugar, cocaine or street-produced amphetamines, seeking relief from their sensations of motorical unease and to disturb their rationalising and thinking (Downs, 2013). Using these substances subjectively improves their abilities, reducing the undesired and unpleasant sensations emanating from the ADHD, possibly even creating enjoyable and desirable moods. The resulting problem is, this self-medication causes troubles in many aspects, detectable only gradually after longer periods of consumption. What starts as an effort to paliate the undesirable symptoms of ADHD and other effects thereof, progressively becomes seeking a solution to harmful consumption of marihuana and, in extreme cases, additiction to cannabinoids (Jensen, 2013). OBJECTIVES: The purpose of this thesis is to analyse adult ADHD, regardless of whether they have been diagnosed, yet with perduring symptoms, and who have never been medicated and now use marihuana as self-medication. The main objective is to determine whether respondents subjectively realise when cannabis helps them to relieve their internal unease and when not. Besides, it is also to learn if we can...
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